佛山地区学龄期儿童Hp感染流行病学特征及与儿童生长发育关系的研究

何昀; 黄为民; 刘志刚; 罗威耀; 林青梅; 叶星光; 廖旺; 何小城

doi:10.3969/j.issn.1671-038X.2021.05.09

佛山地区学龄期儿童Hp感染流行病学特征及与儿童生长发育关系的研究

- 1. 南方医科大学附属佛山市妇幼保健院儿科(广东佛山, 528000);
- 2. 南方医科大学第一临床医学院

详细信息

通讯作者: 黄为民,E-mail:xuemei322@126.com

中图分类号: R573

收稿日期: 2021-02-01

Epidemiological characteristics of Hp infection in school-age children in Foshan area and its relationship with children’s growth and development

- 1. Department of Pediatrics, Foshan Maternal and Child Health Hospital, Southern Medical University, Foshan, 528000, China;
- 2. The First Clinical College of Southern Medical University

More Information

Corresponding author: HUANG Wei-min, E-mail: xuemei322@126.com

Received Date: 01 February 2021

摘要

摘要: 目的:探究佛山地区学龄期儿童Hp感染流行病学特征及与儿童生长发育的关系。方法:通过三阶段抽样法选取2019年1月-2020年6月于佛山地区小学就读的一~六年级学龄期儿童共1200例,采用尿素¹³C呼气试验方法对研究对象进行Hp感染检测,并结合问卷调查结果及临床资料进行统计学分析。结果:1200名学龄儿童Hp总感染率为33.58%;男性Hp感染率(32.26%)与女性Hp感染率(34.86%)差异无统计学意义(P>0.05),农村儿童Hp感染率(40.44%)明显高于城镇儿童(26.82%),差异有统计学意义(P<0.05);6~8岁儿童Hp感染率(22.76%)明显低于8~10岁儿童(33.01%)和10~12岁儿童(44.84%),差异有统计学意义(P<0.05),8~10岁儿童Hp感染率明显低于10~12岁儿童,差异有统计学意义(P<0.05);Hp感染儿童父母身高、出生体重、足月率、母乳喂养率与Hp未感染儿童差异无统计学意义(P>0.05),Hp感染儿童WHZ<-1发生率、HAZ<-1发生率、WAZ<-1发生率均远高于未感染儿童(P<0.05)。结论:学龄期儿童Hp感染与其性别并无明显关系,农村儿童Hp感染率明显高于城镇儿童,学龄期儿童Hp感染率随着其年龄的增加而增加,且对于儿童的生长发育情况有明显影响。
- 幽门螺杆菌 /
- 儿童 /
- 流行病学 /
- 生长 /
- 发育
Abstract: Objective: To explore the epidemiological characteristics of Helicobacter pylori infection in school-age children in Foshan and its relationship with growth and development.Methods: We used a three-stage sampling method to select a total of 1200 cases of school-age children in grades one to six who were studying in primary schools in Foshan from January 2019 to June 2020, and then used the ¹³C-UBT method to test the subjects for Hp infection, combined the results of the questionnaire survey and clinical data for statistical analysis.Results: The total Hp infection rate among 1200 school-age children was 33.58%.The total Hp infection rate of 1200 school-age children was 33.58%;the Hp infection rate of males(32.26%) was not significantly different from that of females(34.86%)(P>0.05), and the Hp infection rate of rural children(40.44%) was significantly higher than that Hp infection rate in urban children(26.82%)(P<0.05); Hp infection rate in children aged 6-8(22.76%) was significantly lower than that in children aged 8-10(33.01%) and Hp infection in children aged 10-12(44.84%)Hp infection rate of children aged 8-10 was significantly lower than that of children aged 10-12(P<0.05).There was no significant difference in the height, weight, full-term rate, breastfeeding rate, and Hp-uninfected children of children with Hp infection(P>0.05).The incidence of Hp-infected children with WHZ<-1,HAZ<-1 and WAZ<-1 was much higher than that of uninfected children(P<0.05).Conclusion: There is no obvious relationship between Hp infection in school-age children and their sex. The Hp infection rate in rural children is significantly higher than that in urban children. The Hp infection rate in school-age children increases with their age and has a significant impact on the growth and development of children.
- Helicobacter pylori /
- children /
- epidemiology /
- growth /
- development

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