基于肠道菌群-肠-脑轴探讨膳食营养对消化心身疾病影响的研究进展

章梦琪; 李金骁; 尚罗锐; 周方园; 杨胜兰

doi:10.3969/j.issn.1671-038X.2023.01.06

基于肠道菌群-肠-脑轴探讨膳食营养对消化心身疾病影响的研究进展

- 1.
  华中科技大学同济医学院附属协和医院中医科(武汉，430022)
- 2.
  华中科技大学同济医学院附属协和医院临床营养科

详细信息

通讯作者: 杨胜兰，E-mail: yangshenglan005@163.com

^Δ 审校者

中图分类号: R259

收稿日期: 2022-12-05

刊出日期: 2023-01-15

Research progress on the effects of dietary nutrition on digestive psychosomatic disorders based on microbiota-gut-brain axis

- 1.
  Department of Traditional Chinese Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China
- 2.
  Department of Clinical Nutrition, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology

More Information

Corresponding author: YANG Shenglan, E-mail: yangshenglan005@163.com

Received Date: 05 December 2022

Publish Date: 15 January 2023

摘要

摘要: 消化心身疾病是临床发病率最高的心身疾病，其发病机制和治疗一直备受关注。随着医学模式的转变，肠道菌群-肠-脑轴理论的出现为消化心身疾病的探索提供了可能的内在机制，肠道菌群是该机制的核心。饮食及其营养成分既是致病因素，又是调节肠道菌群的最关键因素。该文通过检索近年来最新文献，基于肠道菌群-肠-脑轴探讨肠道菌群与消化心身疾病、膳食营养之间的关系，以及宏量营养素、微生态制剂干预肠道菌群在消化心身领域的研究进展并提出展望。
- 肠道菌群 /
- 肠道菌群-肠-脑轴 /
- 膳食 /
- 营养 /
- 消化心身疾病
Abstract: Digestive psychosomatic disorders are the most common psychosomatic disorders in clinical practice, and research into their pathogenesis and treatment have been considerable. With the evolution of medical models, the theory of the microbiota-gut-brain axis has provided a possible internal mechanism for the exploration of digestive psychosomatic disorders, and gut microbiota is the core of this mechanism. In addition to being pathogenic, diet and dietary nutrients are the most critical factors in regulating gut microbiota. Based on the microbiota-gut-brain axis, this review discusses the relationship between gut microbiota, digestive psychosomatic disorders and dietary nutrition, as well as the research progress of the intervention of gut microbiota by macronutrients and microecological agents in psychosomatic domain of the digestive system by searching the latest literature in recent years, and puts forward prospects.
- gut microbiota /
- microbiota-gut-brain axis /
- diet /
- nutrition /
- digestive psychosomatic disorders

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