Hp相关性慢性胃炎中医证型分布及血清胃泌素-17水平的相关性分析

阮博文; 周晓玲; 李裕珍; 潘益巧; 王月明; 钟镇康; 陈作海; 张志杰

doi:10.3969/j.issn.1671-038X.2021.03.02

Hp相关性慢性胃炎中医证型分布及血清胃泌素-17水平的相关性分析

- 1 广西中医药大学研究生院(南宁, 530000);
- 2 柳州市中医医院消化科
基金项目:
柳州市肝病临床医学研究中心项目(No:2018AF10503)

2019年研究生教育创新计划项目(No:YCSY20190069)

详细信息

通讯作者: 周晓玲,E-mail:ZXL_LZ@163.com

中图分类号: R573

收稿日期: 2020-09-10

Correlation between Traditional Chinese Medicine syndrome type distribution and G-17 level in Hp related chronic gastritis

- 1 Graduate School of Guangxi University of Traditional Chinese Medicine, Nanning, 530000, China;
- 2 Department of Gastroenterology, Liuzhou Traditional Chinese Medicine Hospital

More Information

Corresponding author: ZHOU Xiaoling, E-mail: ZXL_LZ@163.com

Received Date: 10 September 2020

摘要

摘要: 目的:探讨Hp相关性慢性胃炎中医证型分布及各证型间胃泌素-17(G-17)水平的相关性。方法:收集Hp相关性慢性胃炎患者400例,按慢性胃炎中医辨证分为脾胃湿热证、脾胃虚寒证、寒热错杂证、肝胃不和证、胃阴不足证、胃络瘀阻证6个证型,并测各证型内患者G-17水平。结果:Hp相关性慢性胃炎各证型例数由高到低分别为:脾胃湿热证>脾胃虚寒证>寒热错杂>肝胃不和证>胃阴不足证>胃络瘀阻证,差异有统计学意义(P<0.05),其中Hp相关性慢性萎缩性胃炎以脾胃虚寒证例数最多,而Hp相关性慢性非萎缩性胃炎以脾胃湿热证例数最多。G-17水平比较,慢性非萎缩性胃炎患者大于慢性萎缩性胃炎患者;各证型间G-17水平由高到低分别为:胃阴不足证>胃络瘀阻证>肝胃不和证>寒热错杂证>脾胃湿热证>脾胃虚寒证,差异有统计学意义(P<0.05),而胃阴不足证与胃络瘀阻证比较,差异无统计学意义(P>0.05);Hp相关性慢性萎缩性胃炎各证型患者低于Hp相关性慢性非萎缩性胃炎各证型患者,差异有统计学意义(P<0.05)。结论:Hp相关性慢性胃炎的中医证型分布存在着一定的规律,且各证型间与G-17水平有一定的内在联系,可为中医辨证提供参考,并指导临床遣方用药。
- 幽门螺杆菌 /
- 慢性胃炎 /
- 中医证型 /
- 胃泌素-17
Abstract: Objective: To investigate the distribution of Traditional Chinese Medicine syndromes of Helicobacter pylori(Hp)-related chronic gastritis and the correlation of G-17 level among different.Methods: Four hundred patients with Hp-related chronic gastritis were collected and classified according to TCM syndrome differentiation of chronic gastritis into 6 syndrome types,namely dampness-heat syndrome of spleen and stomach,deficiency and cold syndrome of spleen and stomach, mixed cold and heat syndrome,disharmony between liver and stomach, deficiency of stomach Yin and obstruction of stomach collaterals,and the G-17 level of each syndrome type was measured.Results: Hp correlation between chronic atrophic gastritis type each card number from high to low: taste hot and damp card > spleen deficiency cold syndrome > fever>mixed liver stomach with certificate > stomach Yin deficiency syndrome > gastric stasis winding resistance,the difference was statistically significant(P<0.05),of which Hp correlation with spleen deficiency chronic atrophic gastritis cold syndrome, the largest and Hp correlation between chronic atrophy gastritis to taste the hot and humid card number Compared with the G-17 level,patients with chronic non-atrophic gastritis were larger than those with chronic atrophic gastritis. The G-17 level among all syndrome types was from high to low: syndrome of deficiency of stomach Yin=syndrome of stasis in stomach collaterals > syndrome of disharmony between liver and stomach > syndrome of cold and heat disorder > syndrome of dampness-heat of spleen and stomach > syndrome of deficient cold of spleen and stomach,the difference was statistically significant(P<0.05), while syndrome of deficiency of stomach collaterals and stasis in stomach was not statistically significant(P>0.05).Patients with each syndrome type of Hp-related. Chronic atrophic gastritis were lower than those with each syndrome type of Hp-related chronic atrophic gastritis, and the difference was statistically significant(P<0.05).Conclusion: The distribution of TCM syndromes of Hp-related chronic gastritis is regular,and there is a certain internal relation between the TCM syndromes and the G-17 level, which provides a reference for the differentiation of TCM syndromes and guides the clinical use of latent prescriptions.
- Helicobacter pylori /
- chronic gastritis /
- Traditional Chinese Medicine syndrome /
- G-17

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