Therapeutic observation of point-application of spleen-strengthening and kidney-warming cataplasm in the treatment of diarrhea-predominant irritable bowel syndrome
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摘要: [目的]观察健脾温肾巴布剂穴位贴敷治疗腹泻型肠易激综合征 (IBS-D) 的临床疗效。[方法]将146例脾肾阳虚型IBS-D患者随机分为观察组和对照组, 观察组使用健脾温肾巴布剂穴位贴敷治疗, 对照组使用安慰剂穴位贴敷治疗, 疗程4周, 随访4周。采用IBS症状严重程度量表 (IBS-SSS) 积分、中医证候积分评估2组患者总体症状疗效、证候疗效。[结果]治疗4周后, 观察组患者IBS-SSS表中腹痛、腹痛天数、腹胀、排便满意度、肠道症状对生活的干扰积分较治疗前明显下降 (P<0.05), 且较对照组下降更多 (P<0.05)。治疗4周后观察组中医证候积分较治疗前明显下降 (P<0.05), 且较对照组下降更多 (P<0.05)。观察组、对照组IBS-SSS总有效率分别为93.24%和50.68%, 中医证候总有效率分别为89.04%和42.46%。[结论]健脾温肾巴布剂穴位贴敷法治疗IBS-D能缓解临床症状, 具有良好的临床疗效。Abstract: [Objective]To observe the clinical effect of point-application of spleen-strengthening and kidney-warming cataplasm on diarrhea-predominant irritable bowel syndrome (IBS-D).[Methods]146 IBS-D cases with spleen-kidney yang deficiency were randomly divided into the observation group and the control group.These two groups were treated with point-application of spleen-strengthening and kidney-warming cataplasm and placebo respectively for a four-weeks treatment, and followed up for 4 weeks after the treatment.The scores of the IBS symptom severity scale (IBS-SSS), TCM syndrome index, overall symptom efficacy, and syndrome efficacy were all observed.[Results]After 4 weeks of treatment, the abdominal pain, the days of onset of abdominal pain, abdominal distension, satisfaction with defecation and the disturbance score of intestinal symptoms on daily life of IBS-D patients in observation group were significantly decreased (P<0.05), and the reduction is more significant than that in control group with statistical differrence (P<0.05).After 4 weeks of treatment, TCM syndrome scores in the observation group decreased significantly after the treatment (P<0.05), and the decline was more remarkable than that in the control group (P<0.05).The total effective rates of IBS-SSS in the observation group and the control group were 93.24% and 50.68% respectively.The total effective rates of TCM syndrome were 89.04% and 42.46% respectively.[Conclusion]Point-application of spleen-strengthening and kidney-warming cataplasm for IBS-D can effectively relieve clinical symptom.
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