Effect of Pluse-taking therapy of Zhouyixiangshu on symptom score and basal metabolic rate in patients with functional dyspepsia
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摘要: [目的]观察周易象数切脉疗法对功能性消化不良（Functional dyspepsia，FD）患者症状评分及基础代谢率的影响，并探讨二者的相关性。[方法]观察对象为160例FD合格受试者。治疗组80例行周易象数切脉疗法治疗，莫沙必利西药组80例予枸橼酸莫沙必利分散片口服治疗，检测2组治疗前后症状评分及基础代谢率，并对2者进行相关性分析。[结果]治疗前，2组患者的基础代谢率比较差异无统计学意义（P<0.05），治疗第7 d、第14 d、第21 d周易象数切脉治疗组基础代谢率高于治疗前，莫沙必利西药组治疗第7 d、第14 d、第21 d基础代谢率与治疗前比较，差异无统计学意义（P>0.05）；周易象数切脉疗法的总有效率为96.67%，莫沙必利西药组的总有效率为86.67%，2组比较差异有统计学意义（P<0.05）；2组治疗后中医证候评分均下降，且周易象数切脉疗法组下降更明显（P<0.05）；采用Spearman相关性分析，结果显示，症状评分与基础代谢率呈负相关（P=0.005）。[结论]周易象数切脉疗法可有效改善消化不良患者症状，其机制可能与改善患者的基础代谢率有关。Abstract: [Objective] To observe the effect of pluse-taking therapy of Zhouyixiangshu on symptom score and basal metabolic rate in patients with functional dyspepsia(FD), and to explore the correlation between them.[Methods] A total of 160 FD subjects were observed.80 patients in the treatment group were treated with pluse-taking therapy of Zhouyixiangshu, 80 cases of mosapride western medicine group were treated with mosapride citrate dispersible tablet, and the symptom score and basal metabolic rate were measured before and after treatment.And the correlation between symptom score and basal metabolic rate was analyzed.[Results] Before treatment, the basal metabolic rate of the two groups was statistically significant(P<0.05).The basal metabolic rate of the treatment group was higher than that before treatment on the 7 th day, the 14 th day and the 21 st day, There was no significant difference in the basal metabolic rate between the 7 th day, the 14 th day and the 21 st day(P>0.05).The total effective rate was 16.67%(P<0.05).The scores of TCM syndromes were decreased in both groups after treatment, and the incidence of TCM syndromes decreased significantly(P<0.05), and the difference had statistically significance(P<0.05).Using Spearman correlation analysis, the results showed that the symptom score was negatively correlated with basal metabolic rate(P=0.005).[Conclusion] The pluse-taking therapy of Zhouyixiangshu may be effective in improving the symptoms of dyspepsia patients, and the mechanism may be related to the improvement of basal metabolic rate in patients.
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