Clinical effect of herbal compound Danshishuhoufang in patients with direct peroral cholangioscopy by using an ultraslim upper endoscope
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摘要: [目的]观察口服中药胆石术后方在经口直接胆道镜胆总管取石术后的临床疗效。[方法]将60例患者随机分为中药组和对照组,对照组仅行经口直接胆道镜取石治疗,中药组则在经口直接胆道镜取石后第1 d至第4 d口服中药胆石术后方,观察2组相关指标的变化并进行统计学分析。[结果]中药组患者部分临床表现及相关血生化改善情况优于对照组,胆汁引流量大于对照组,胆道冲洗液潜血阳性率及胆管炎发生率低于对照组,且均具有统计学意义。[结论]胆石术后方具有利胆通腑、清热化湿、凉血止血功效。能减少或减轻胆道感染、胆道出血、胰腺炎或高淀粉酶血症等术后并发症的发生。Abstract: [Objective] To observe the therapeutic effect of herbal compound Danshishuhoufang in patients with direct peroral cholangioscopy(DPOC)by using an ultraslim upper endoscope. [Methods]Sixty participants were randomly assigned to an herbal compound group or a control group.The former were treated with herbal compound Danshishuhoufang from the 1st to the 4th day after performing DPOC,whereas the latter had no such treatment after DPOC.The clinical information and serum data were collected to perform a statistical analysis between the two groups.[Results]We observed that patients who had received herbal compound after DPOC exhibited positive effects-the clinical symptoms,serum biochemical levels and biliary drainage were better improved compared to the control group(P<0.05).We also found that in incidence of biliary irrigative solution occult blood and cholangitis,the experimental group is lower than the comparison group(P<0.05).[Conclusion]These findings suggest that the herbal compound Danshishuhoufang might play an important role in normalizing the secretion and discharge of bile,clearing away heat and eliminating dampness,and cooling blood and hemostasis.It provides new therapeutic strategies for reducing the adverse outcomes post DPOC,such as cholangitis,bleeding,edematous pancreatitis,and increased pancreatic amylase.
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Key words:
- choledocholithiasis /
- DPOC /
- Danshishuhoufang
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