The clinical application of early enteral nutrition on nutritional status and liver function in patients after gastrectomy
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摘要: [目的]探讨早期肠内营养应用在胃切除术患者对营养状态和肝脏功能的影响效果及临床应用价值。[方法]对我院进行胃切除手术患者采用随机数字表法分为观察组和对照组,对照组进行常规营养支持,观察组进行早期肠内营养支持,观察两组临床治疗效果。[结果]观察组手术后血清总蛋白(73.53±7.98)g/L,血清白蛋白(45.86±4.89)g/L;对照组手术后血清总蛋白(67.13±2.42)g/L,血清白蛋白(38.79±1.71)g/L,组间对比差异有统计学意义(P<0.05)。观察组手术后总胆红素(9.11±2.74)μmol/L,丙氨酸转氨酶(25.09±5.70)U/L,天冬氨酸转氨酶(18.43±4.51)U/L;对照组手术后总胆红素(25.39±6.54)μmol/L,丙氨酸转氨酶(49.79±.10.48)U/L,天冬氨酸转氨酶(45.79±11.38)U/L,组间对比差异有统计学意义(P<0.05)。观察组术后发生吻合口瘘1例,切口感染2例,下肢静脉血栓1例;对照组术后发生吻合口瘘9例,切口感染13例,下肢静脉血栓7例,组间对比差异有统计学意义(P<0.05)。[结论]早期肠内营养应用在胃切除术患者中能够改善患者术后营养状态和肝脏功能,降低手术后并发症发生率,改善患者临床预后,值得在临床上推广应用。Abstract: [Objective]To discuss the application of early enteral nutrition in patients with gastric resection on the nutritional status and the liver function and clinical application value.[Methods]Gastric resection surgery patients in our hospital were randomly divided into observation group and control group.Control group received routine nutritional support,while observation group received early enteral nutrition support.Clinical curative effect was observed in the two groups.[Results]After the operation,serum total protein was(73.53±7.98)g/L,and serum albumin was(45.86±4.89)g/L in observation group,which was respectively(67.13±2.42)g/L and(38.79±1.71)g/L in control group.There was significant difference between the two groups(P<0.05).The postoperative total bilirubin in observation group was(9.11±2.74)μmol/L,alanine aminotransferase was(25.09±5.70)U/L,and aspartate aminotransferase was(18.43±4.51)U/L,while in control group,they were respectively(25.39±6.54)μmol/L,49.79±10.48)U/L,and(45.79±11.38)U/L,showing significant differences between the two groups(P<0.05).In observation group,there was 1 case of postoperative anastomotic fistula,2 cases of incision infection,and 1 case of lower limb venous thrombosis.In control group,9 cases had anastomotic fistula,13 had postoperative infection of incision,and 7 cases had lower extremity venous thrombosis.Differences between the two groups were statistically significant(P<0.05).[Conclusion]Application of early enteral nutrition in patients with gastric resection can improve postoperative patients nutrition status and liver function,reduce the incidence of complications after the operation,and improve the prognosis of patients.
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Key words:
- Early enteral nutrition /
- gastrectomy /
- Nutritional status /
- Liver function
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