Clinical efficacy of Banxia Xiexin Decoction combined with acupoint sticking on functional dyspepsia and its effects on serum motilin
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摘要: [目的]探讨半夏泻心汤加味配合穴位贴敷治疗功能性消化不良(FD)的临床疗效及对血清胃动素(MTL)的影响。[方法]选取接受治疗的FD患者114例,随机分为观察组和对照组各57例,观察组以半夏泻心汤加味配合穴位贴敷治疗,对照组运用枸橼酸莫沙必利分散片进行治疗,观察疗效及治疗前后血清MTL的水平。[结果]经治疗4周后,总有效率观察组为87.7%,对照组的75.4%,2组总有效率比较差异有统计学意义(P＜0.05);2组治疗后中医症状积分比较,差异有统计学意义(P＜0.05)。2组内治疗前后MTL比较,差异有统计学意义(P＜0.01)。2组治疗后MTL比较,差异有统计学意义(P＜0.05),观察组优于对照组。[结论]半夏泻心汤加味配合穴位贴敷治疗FD可升高血清MTL水平,促进胃肠道蠕动,能有效改善症状,临床疗效明确。Abstract: [Objective] To study the treatment efficacy of Banxia Xiexin Decoction(BXD)combined with acupoint sticking on functional dyspepsia and its effects on serum motilin.[Methods] 114 patients with functional dyspepsia were randomly divided into two groups(57 patients in each):observation group and control group.The former was treated with BXD combined with acupoint sticking,the latter was given Mosapride Citrate Dispersible Tablets.Both were observed for four weeks.[Results] After four weeks’treatment,the efficiency of the observation group and the control group was 87.7% and 75.4% respectively,showing statistical significance(P＜0.05).Symptom scores after the treatment also showed significant difference between the two groups(P＜0.05).In both groups MTL was significantly improved after the treatment(P＜0.01),the effect of the observation group was better than that of the control group.[Conclusion] BXD combined with acupoint sticking for the treatment of FD could increase the level of serum MTL and promote gastrointestinal peristalsis,resulting in the improvement of symptoms with good clinical effect.
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Key words:
- Banxia Xiexin Decoction(BXD) /
- acupoint sticking /
- functional dyspepsia /
- motilin
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[1] 李建平, 蔡翠珠, 刘德喜.健脾调中消痞方治疗脾虚气滞型功能性消化不良临床疗效观察[J].广州中医药大学学报, 2015, 32(5):817-820.
[2] KHOO J, RAYNER C K, FEINLE-BISSET C, et al.Gastrointestinal hormonal dysfunction in gastroparesis and functional dyspepsia[J].Neurogastroenterol Motil, 2010, 22:1270-1278.
[3] 罗马委员会.功能性胃肠病罗马Ⅲ诊断标准[J].胃肠病学, 2006, 11(12):761-765.
[4] 郑筱萸.中药新药临床研究指导原则[M].北京:中国医药科技出版社, 2005:134-137.
[5] 中华中医药学会脾胃病分会.消化不良中医诊疗共识意见(2009)[J].中国中西医结合杂志, 2010, 30(5):533-537.
[6] 陈海山, 龚锦容, 黄朝忠, 等.功能性消化不良与胃黏膜肥大细胞、血浆胃动素的关系[J].胃肠病学, 2015, 20(9):533-537.
[7] 王强, 李哲华, 张雁.半夏泻心汤加减治疗功能性消化不良的临床分析[J].中医临床研究, 2012, 4(11):69-71.
[8] 许卫华, 姚树坤, 李妮娇, 等.功能性消化不良中医辨证论治的临床疗效观察[J].中国中西医结合消化杂志, 2013, 21(5):225-228.
[9] 樊春华, 胡瑾君, 陈文剑.健脾疏肝行气法配合穴位注射治疗脾虚气滞型功能性消化不良临床观察[J].新中医.2015, 47(3):211-213.
[10] 李欣, 林琳, 魏玮.半夏泻心汤加减治疗功能性消化不良60例临床观察[J].中华中医药杂志, 2013, 28(4):876-878.
[11] 樊春华, 胡瑾君, 陈文剑.香砂六君子汤配合贴敷治疗脾胃虚弱型功能性消化不良的疗效分析[J].陕西中医.2015, 36(1):17-19.
[12] 胡冬青, 曹志群.穴位贴敷疗法在消化系统疾病中的应用[J].河南中医, 2012, 32(9):1248-1251.
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