加味葛根芩连汤结合肛塞清肠栓治疗溃疡性结肠炎的效果观察

卢璐; 袁建业; 费晓燕; 萨金姝; 谢建群

doi:10.3969/j.issn.1671-038X.2013.02.002

加味葛根芩连汤结合肛塞清肠栓治疗溃疡性结肠炎的效果观察

- 1. 上海中医药大学附属龙华医院, 上海 200032;
- 2. 上海中医药大学上海 201203
基金项目:
上海市科委课题（No：08411961300）

详细信息

作者简介:
卢璐,博士,从事中医脾胃病的临床及科研工作

通讯作者: 谢建群,E-mail:xiejianqun@live.cn

中图分类号: R574.62

收稿日期: 2012-09-16

Clinical effects of Modified Gegenqinlian Decoction combined with per rectum Qingchangshuan in the treatment of ulcerative colitis

- 1. Shanghai University of Traditional Chinese Medicine Affiliated Longhua Hospital, Shanghai 200032, China;
- 2. Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China

More Information

Corresponding author: XIE Jian-qun, E-mail: xiejianqun@live.cn

Received Date: 16 September 2012

摘要

摘要: [目的]观察加味葛根芩连汤联合肛塞清肠栓治疗溃疡性结肠炎的临床疗效。[方法]120例轻-中度溃疡性结肠炎患者被随机分为：口服加味葛根芩连汤联合肛塞清肠栓组（L组）、口服加味葛根芩连汤组（G组）、肛塞清肠栓组（Q组）、口服柳氮磺胺吡啶组（S组），每组30例。观察比较各组患者治疗前后症状总积分、黏液脓血便、里急后重等单项症状积分及肠镜下表现积分的变化。[结果]L组能有效改善患者总体症状和肠镜检查所见的病理表现，且优于其他3组疗法，总有效率为96.67%；在改善"里急后重"和"黏液脓血便"症状方面，也较其他3组疗法起效更快。[结论]加味葛根芩连汤联合肛塞清肠栓能有效改善溃疡性结肠炎患者的总体症状和肠镜下病理表现。
- 结肠炎,溃疡性 /
- 加味葛根芩连汤 /
- 清肠栓
Abstract: [Objective] To observe the clinical effects of Modified Gegenqinlian Decoction (MGD) combined with per rectum Qingchangshuan in the treatment of ulcerative colitis(UC).[Methods] One hundred and twenty cases of mild to moderate UC patients were randomly divided into 4 different therapeutic groups (each n=40). Group L was treated by MGD and per rectum Qingchangshuan, Group G was treated by MGD, Group Q was treated by per rectum Qingchangshuan and Group S was treated by sulfasalazine.The clinical effects were evaluated by colonoscopy results and individual symptoms (mucous, purulent discharge and blood in stool, tenesmus i.e.).[Results] The colonoscopy findings and the total scores of symptom changes were effectively improved in Group L, which was superior to the other three groups. The total effective rate was 96.67% in Group L, and the relief of symptoms such as tenesmus, mucus, purulent discharge and bloody stools was particularly faster when compared with other three treatments groups.[Conclusion] MGD combined with per rectum Qingchangshuan could improve the symptoms of UC as well as its pathological findings under colonoscopy.
- ulcerative colitis /
- Modified Gegenqinlian Decoction /
- Qingchangshuan

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参考文献(5)

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