大黄治疗非甾体抗炎药相关消化性溃疡疗效观察

杨光宇; 赵元奎

doi:10.3969/j.issn.1671-038X.2013.02.003

大黄治疗非甾体抗炎药相关消化性溃疡疗效观察

杨光宇^1, ,,
赵元奎²

- 1. 河北省唐山市丰润区中医医院急诊科, 河北唐山 064000;
- 2. 河北省唐山市丰润区第二人民医院, 河北唐山 064000

详细信息

作者简介:
杨光宇,主任医师,从事急诊科工作

通讯作者: 杨光宇,E-mail:yangguangyu72@163.com

中图分类号: R574.1

收稿日期: 2012-10-16

Effect of Rhubarb powder on non-steroidal anti-inflammatory drugs related peptic ulcer

YANG Guang-yu^1, ,,
ZHAO Yuan-kui²

- 1. Department of Emergency, Traditional Chinese Medicine Hospital of Fengrun Area of Tangshan City, Hebei Tangshan 064000, China;
- 2. the Second People's Hospital of Fengrun Area of Tangshan City, Hebei Tangshan 064000, China

More Information

Corresponding author: YANG Guang-yu, E-mail: yangguangyu72@163.com

Received Date: 16 October 2012

摘要

摘要: [目的]观察大黄对非甾体抗炎药（NSAIDs）相关消化性溃疡的疗效。[方法]将NSAIDs相关消化性溃疡96例，分为大黄治疗组（48例）和对照组（48例），对照组采用基础治疗，方法为口服奥美拉唑和清除幽门螺杆菌；大黄治疗组在对照组治疗的基础上加大黄粉口服。观察并比较2组的疗效。[结果]大黄治疗组痊愈19例（39.6%），好转26例（52.4%），无效3例（6.2%），总有效率93.8%；对照组痊愈16例（33.3%），好转22例（45.8%），无效10例（20.8%），总有效率79.2%；经χ²检验，2组差异有统计学意义（P﹤0.05）。[结论]大黄粉与西药结合治疗NSAIDs相关消化性溃疡疗效更优。
- 消化性溃疡 /
- 非甾体抗炎药 /
- 大黄 /
- 幽门螺杆菌
Abstract: [Objective] To observe the effect of rhubarb powder on non-steroidal anti-inflammatory drugs (NSAIDs) related peptic ulcer.[Methods] Ninety-six cases of NSAIDs related peptic ulcer were divided into rhubarb group and control group(48 cases each). The control group was administered with basic treatment such as oral omeprazole and clearance of Helicobacter pylori. The Rhubarb group was given oral Rhubarb besides the basic treatment. Therapetic effect of the two groups were observed.[Results] In the Rhubarb treatment group, 19 cases were cured (39.6%), 26 improved (52.4%), 3 invalid (6.2%), the total efficiency was 93.8%. In the control group, 16 cases were cured (33.3%), 22 improved (45.8%), 10 invalid (20.8%), the total efficiency was 79.2%. There was significant difference between the two groups (P< 0.05).[Conclusion] Rhubarb powder combined with western medicine had good effect on NSAIDs related peptic ulcer.
- peptic ulcer /
- non-steroidal anti-inflammatory drugs /
- Rhubarb /
- helicobacter pylori

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