益气养阴润肠方对小鼠肠道动力的影响

王云峰

doi:10.3969/j.issn.1671-038X.2012.05.008

益气养阴润肠方对小鼠肠道动力的影响

王云峰^,

- 江苏省昆山市第二人民医院消化科, 江苏昆山 215300

详细信息

作者简介:
王云峰,医学硕士,住院医师;研究方向:中医脾胃病

通讯作者: 王云峰,E-mail:wang1985116@126.com

中图分类号: R442.2;R574.62

收稿日期: 2012-03-09

Experimental study of of Yiqiyangyinrunchang decoction on the mouse intestinal motility

WANG Yun-feng^,

- Department of Digestive Diseases, the Second People's Hospital of Kunshan City, Jiangsu Province, Kunshan 215300, China

More Information

Corresponding author: WANG Yun-feng, E-mail: wang1985116@126.com

Received Date: 09 March 2012

摘要

摘要: [目的]研究益气养阴润肠方对小鼠肠道动力的影响。[方法]小鼠40只，随机分为益气养阴润肠方高剂量（47.84 g·kg^-1·d^-1）组、中剂量（23.92 g·kg^-1·d^-1）组、低剂量（11.96 g·kg^-1·d^-1）组、正常组、新斯的明组（阳性组）。实验7 d后处死所有小鼠，测碳末推进率。[结果]阳性组、益气养阴润肠方各剂量组的碳末推进率均明显提高，与正常组比较，差异有统计学意义（P<0.0 1）。[结论]中医益气养阴润肠法汤剂对小鼠肠道动力有明显的促进作用。
- 便秘 /
- 益气养阴润肠 /
- 肠道动力 /
- 实验研究
Abstract: [Objective] To study the effect of the decoction of Yiqiyangyinrunchang on the mouse intestinal motility.[Methods] Forty mice were randomly divided into Yiqiyangyinrunchang decoction of high(47.84 g·kg^-1·d^-1),medium(23.92 g·kg^-1·d^-1),low dose group(11.96 g·kg^-1·d^-1),normal group(0 g·kg^-1·d^-1),positive group(Neostigmine,used in the last day,0.00013 g·kg^-1·d^-1).Seven days after the administration, the rate of carbon propelling was measured.[Results] Compared with the normal group,the positive group,Yiqiyangyinrunchang low dose group,middle dose and high dose group showed significantly increased carbon propelling,and had a statistically significant difference(P<0.01).[Conclusion] The decoction of Yiqiyangyinrunchang has significant promotion on intestinal motility of the mouse.
- constipation /
- decoction of Yiqiyangyinrunchang /
- intestinal motility /
- experimental study

HTML全文

参考文献(9)

[1]	喻玲.调和肝脾法治疗功能性便秘[J].现代诊断与治疗,2007,18(5):282-282.
[2]	WHITE W B,JOHNSON M F,ANDERS R J,et al.Safety of controlled-onset extended-release verapamil in middle-aged and older patients with hypertention and coronary artery disease[J].Am Heart J,2001,142(6):1010-1010.
[3]	郭惠学,周怀力,陈鸿江,等.功能性便秘与结肠黑变病的关系探讨[J].现代消化及介入,2003,8(1):30-31.
[4]	谢鸣.方剂学[M].北京:人民卫生出版社,2002:189-189.
[5]	马伯艳,李冀,肖洪彬.《温病条辨》增液汤治疗津亏液竭便秘的实验研究[J].江苏中医药,2007,39(5):57-58.
[6]	王震,宋健.玄参多糖对运动小鼠组织抗氧化能力的影响[J].食品科学,2010,31(17):385-387.
[7]	高学敏.中药学[M].北京:中国中医药出版社,2002:503-503.
[8]	祝巍,张玉萍.HPLC法测定地黄不同炮制品种梓醇的含量[J].江西中医药,2008,39(1):71-71.
[9]	徐文豪,邱声样,沈连忠,等.肉苁蓉和盐肉苁蓉化学成分和药理作用的比较[J].中草药,1995,26(3):143-146.