Discussion on the treatment of polycystic liver disease patients with recurrent fever via Traditional Chinese Medicine based on the theory of "emission therapy of fire stagnancy"
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摘要: 多囊肝是一种遗传性疾病,感染发热为其常见的并发症之一,目前西医以抗感染治疗为主,但反复使用抗生素会导致耐药菌形成,为进一步用药增加了难度;另一方面,反复的感染发热会导致患者免疫力低下甚至病情迅速恶化。中药联合抗生素治疗在缓解该病患者全身症状以及提高生活质量方面具有相对的优势,本病的中医病机为“正气虚衰、清阳不升、气机郁滞、郁火内生”。本文通过探讨多囊肝的中医病机,以及基于“火郁发之”理论的治疗思路,为中医药治疗多囊肝反复感染发热提供思路借鉴。Abstract: Polycystic liver is a genetic disease in clinical, which is one of the common complications of infection with fever. At present, western medicine treatment mainly focuses on anti-infection treatment, but the use of antibiotics repeatedly can lead to the formation of resistant bacteria, To some extent, it increases the difficulty of taking the medication; On the other hand, repeated infection and fever can lead to patients' low immunity and even rapid deterioration of their condition. Chinese herbs combined with antibiotic therapy have advantages in relieving systemic symptoms and improving the quality of life, The Traditional Chinese Medicine pathogenesis of this disease is "positive Qi deficiency, Qingyang does not rise, Qi stagnation, depression and fire endogenous".This paper discusses the Traditional Chinese Medicine pathogenesis of polycystic liver and the treatment idea of "emission therapy of fire stagnancy", which provides a reference for the treatment of recurrent polycystic liver with fever.
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[1] van Aerts R, van de Laarschot L, Banales JM, et al.Clinical management of polycystic liver disease[J]. J Hepatol, 2018, 68(4):827-837. doi: 10.1016/j.jhep.2017.11.024
[2] European Association for the Study of the Liver.EASL clinical practice guide lines on management of cystic liver diseases[J]. J Hepatol, 2022;77(4):1083-1108. doi: 10.1016/j.jhep.2022.06.002
[3] Masyuk T, Masyuk A, Trussoni C, et al.Autophagy-mediated reduction of miR-345 contributes to hepatic cystogenesis inpolycystic liver disease[J]. JHEP Rep, 2021, 3(5):100345. doi: 10.1016/j.jhepr.2021.100345
[4] Masyuk T, Masyuk A, LaRusso N.Polycystic Liver Diseases:genetics, Mechanisms, and Therapies[M]. In:Arias IM, Alter HJ, Boyer JL, et al, editors.The Liver:Biology and Pathobiology.6aed.Hoboken(NJ):Wiley-Blackwell, 2020:408-421.
[5] Ongaro M, Bronstein FN, Goossens N, et al.[Polycystic liver disease][J]. Rev Med Suisse, 2022, 18(793):1599-1605.
[6] Bae KT, Tao C, Feldman R, et al.Volume Progression and Imaging Classification of Polycystic Liver in Early Autosomal Dominant Polycystic Kidney Disease[J]. Clin J Am Soc Nephrol, 2022, 17(3):374-384. doi: 10.2215/CJN.08660621
[7] Olaizola P, Rodrigues PM, Caballero-Camino FJ, et al.Genetics, pathobiology and therapeutic opportunities of polycystic liver disease[J]. Nat Rev Gastroenterol Hepatol, 2022, 19(9):585-604. doi: 10.1038/s41575-022-00617-7
[8] Zhang ZY, Wang ZM, Huang Y.Polycystic liver disease:classification, diagnosis, treatment process, and clinical management[J]. World J Hepatol, 2020, 12(3):72-83. doi: 10.4254/wjh.v12.i3.72
[9] Wong MY, McCaughan GW, Strasser SI.An update on the pathophysiology and management of polycystic liver disease[J]. Expert Rev Gastroenterol Hepatol, 2017, 11(6):569-581. doi: 10.1080/17474124.2017.1309280
[10] Masyuk AI, Masyuk TV, Trussoni CE, et al.Autophagy promotes hepatic cystogenesis in polycystic liver disease by depletion of cholangiocyte ciliogenic proteins[J]. Hepatology, 2022, 75(5):1110-1122. doi: 10.1002/hep.32298
[11] 田代华.黄帝内经素问[M]. 北京:人民卫生出版社, 2005:60-60.
[12] 马烈光, 张新渝.黄帝内经:素问[M]. 成都:四川科学技术出版社, 2008:730-730.
[13] 何梦瑶.医碥[M]. 上海:上海科学技术出版社, 1982:62-62.
[14] 张景岳.景岳全书[M]. 北京:中国医药科技出版社, 2011:142-145.
[15] 尤怡.金匮要略心典[M]. 太原:山西科学技术出版社, 2008:82-82.
[16] 李用粹.证治汇补[M]. 北京:人民卫生出版社, 2006:103-104.
[17] 陈晓乐, 禄保平.《脾胃论》方治疗功能性发热30例疗效观察[J]. 国医论坛, 2015, 30(6):38-39. https://www.cnki.com.cn/Article/CJFDTOTAL-GYLT201506025.htm
[18] 沈贤敏, 葛惠男.李杲内伤热中证浅探[J]. 现代中医药, 2015, 35(2):37-37, 45. https://www.cnki.com.cn/Article/CJFDTOTAL-XDZY201502018.htm
[19] 潘绍林, 马成双.李东垣应用风药特点分析[J]. 实用中医药杂志, 2012, 28(3):223-223. https://www.cnki.com.cn/Article/CJFDTOTAL-ZYAO201203053.htm
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