慢性萎缩性胃炎发病机制的研究进展

付阳茜; 韩旭; 梁硕; 林芳冰

doi:10.3969/j.issn.1671-038X.2023.06.16

慢性萎缩性胃炎发病机制的研究进展

- 北京中医药大学东直门医院消化科(北京，100700)
基金项目:
国家重点研发计划项目(No：2018YFC1704100，No：2018YFC1704101)

详细信息

通讯作者: 林芳冰，E-mail：linfangbing@163.com

^Δ审校者

中图分类号: R256

收稿日期: 2023-01-12

刊出日期: 2023-06-15

Advances in the pathogenesis of chronic atrophic gastritis

- Department of Gastroenterology, Dongzhimen Hospital, Beijing University of Traditional Chinese Medicine, Beijing, 100700, China

More Information

Corresponding author: LIN Fangbing, E-mail: linfangbing@163.com

Received Date: 12 January 2023

Publish Date: 15 June 2023

摘要

摘要: 慢性萎缩性胃炎属于胃癌的癌前疾病状态，是炎-癌转化的发生关口，近年来患病率呈上升且有年轻化趋势，严重威胁人类生活健康。目前慢性萎缩性胃炎的发病机制尚未明确统一，研究发现慢性萎缩性胃炎发病与幽门螺杆菌感染、自身免疫反应异常、胆汁反流和胃内非幽门螺杆菌菌群等相关。笔者查阅国内外相关文献资料，整理慢性萎缩性胃炎的相关发病机制，以供学习交流。
- 慢性萎缩性胃炎 /
- 发病机制 /
- 幽门螺杆菌 /
- 自身免疫反应异常 /
- 胆汁反流 /
- 胃内非幽门螺杆菌菌群
Abstract: Chronic atrophic gastritis is a precancerous disease state of gastric cancer, which is the key to the occurrence of inflammatory-cancer transformation. In recent years, the prevalence rate is on the rise and tends to be younger, which seriously threatens human life and health. At present, the pathogenesis of chronic atrophic gastritis has not been clearly unified. Studies have found that the pathogenesis of chronic atrophic gastritis is related to helicobacter pylori infection, abnoral autoimmune reaction, bile reflux and non-helicobacter pylori flora in the stomach. The author consulted relevant literature at home and abroad to sort out the pathogenesis of chronic atrophic gastritis for learning and communication.
- chronic atrophic gastritis /
- pathogenesis /
- Helicobacter pylori /
- abnoral autoimmune reaction /
- bile reflux /
- non-Helicobacter pylori Helicobacter

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