Chinese expert consensus on diagnosis and treatment of postoperative gastroparesis syndrome in cancer patients with Traditional Chinese and Western Medicine(2022 edition)
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摘要: 术后胃瘫综合征是腹部手术后常见的并发症之一,一般是由非机械性梗阻因素引起、以胃排空障碍为主要征象的胃动力紊乱综合征,严重影响患者的生活质量,同时导致住院时间延长、住院费用增加。术后胃瘫的发生可能与交感神经激活、胃十二指肠运动失调以及内环境紊乱有关,是包括手术方式和消化道重建在内的多种因素综合作用的结果。胃瘫的诊断以临床表现和影像学等辅助检查发现胃潴留和胃排空延迟为主。目前胃瘫的治疗主要是中西医保守治疗,包括促胃肠动力药物、中药和针灸的联合治疗以及多种治疗措施的综合治疗。Abstract: Postoperative gastroparesis syndrome is one of the common complications after abdominal surgery. It is generally a gastric motility disorder syndrome with gastric emptying disorder as the main symptom caused by non-mechanical obstructive factors, which seriously affects the quality of life of patients, resulting in prolonged hospitalization and increased costs. The occurrence of postoperative gastroparesis may be related to sympathetic nerve activation, gastroduodenal motility disorder, and internal environment disturbance, which is the result of the combined effects of various factors, including surgical approaches and digestive tract reconstruction. The diagnosis of gastroparesis is mainly based on the findings of gastric retention and delayed gastric emptying by clinical manifestations and auxiliary examinations such as imaging. The current treatment plan for gastroparesis is mainly conservative treatment of Traditional Chinese and Western Medicine, including gastrointestinal motility drugs, combined treatment of Traditional Chinese Medicine and acupuncture, and comprehensive treatment of various treatment measures.
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Key words:
- gastric cancer /
- gastroparesis syndrome /
- etiology /
- diagnosis /
- treatment
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[1] 李广华, 叶锦宁, 王昭, 等. 术后胃瘫的治疗进展[J]. 消化肿瘤杂志(电子版), 2018, 10(3): 134-139. doi: 10.3969/j.issn.1674-7402.2018.03.003
[2] Varghese C, Bhat S, Wang TH, et al. Impact of gastric resection and enteric anastomotic configuration on delayed gastric emptying after pancreaticoduodenectomy: a network meta-analysis of randomized trials[J]. BJS Open, 2021, 5(3): zrab035. doi: 10.1093/bjsopen/zrab035
[3] Mukoyama T, Kanaji S, Sawada R, et al. Assessment of risk factors for delayed gastric emptying after distal gastrectomy for gastric cancer[J]. Sci Rep, 2022, 12(1): 15903. doi: 10.1038/s41598-022-20151-5
[4] Degisors S, Caiazzo R, Dokmak S, et al. Delayed gastric emptying following distal pancreatectomy: incidence and predisposing factors[J]. HPB(Oxford), 2022, 24(5): 772-781.
[5] 郭鹏, 马东红, 黄博. 根治性胃大部切除术后残胃排空障碍的研究现状[J]. 中华临床医师杂志(电子版), 2017, 11(9): 1587-1590. https://www.cnki.com.cn/Article/CJFDTOTAL-ZLYD201709030.htm
[6] Grover M, Farrugia G, Stanghellini V. Gastroparesis: a turning point in understanding and treatment[J]. Gut, 2019, 68(12): 2238-2250. doi: 10.1136/gutjnl-2019-318712
[7] Zheng LJ, Ma JC, Fang D, et al. The quantification and assessment of depression and anxiety in patients with postoperative gastroparesis syndrome[J]. Ther Clin Risk Manag, 2018, 14: 551-556. doi: 10.2147/TCRM.S155358
[8] Atieh J, Sack J, Thomas R, et al. Gastroparesis following immune checkpoint inhibitor therapy: a case series[J]. Dig Dis Sci, 2021, 66(6): 1974-1980. doi: 10.1007/s10620-020-06440-x
[9] Camilleri M, Sanders KM. Opiates, the pylorus, and gastroparesis[J]. Gastroenterology, 2020, 159(2): 414-421. doi: 10.1053/j.gastro.2020.04.072
[10] Hasler WL, Wilson LA, Nguyen LA, et al. Opioid use and potency are associated with clinical features, quality of life, and use of resources in patients with gastroparesis[J]. Clin Gastroenterol Hepatol, 2019, 17(7): 1285-1294. e1. doi: 10.1016/j.cgh.2018.10.013
[11] Ramos GP, Law RJ, Camilleri M. Diagnosis and management of gastroparesis[J]. Am J Gastroenterol, 2022, 117(12): 1894-1898. doi: 10.14309/ajg.0000000000002003
[12] Usai-Satta P, Bellini M, Morelli O, et al. Gastroparesis: New insights into an old disease[J]. World J Gastroenterol, 2020, 26(19): 2333-2348. doi: 10.3748/wjg.v26.i19.2333
[13] Orthey P, Yu DH, van Natta ML, et al. Intragastric meal distribution during gastric emptying scintigraphy for assessment of fundic accommodation: correlation with symptoms of gastroparesis[J]. J Nucl Med, 2018, 59(4): 691-697. doi: 10.2967/jnumed.117.197053
[14] Mirbagheri N, Dunn G, Naganathan V, et al. Normal values and clinical use of bedside sonographic assessment of postoperative gastric emptying: a prospective cohort study[J]. Dis Colon Rectum, 2016, 59(8): 758-765. doi: 10.1097/DCR.0000000000000637
[15] Camilleri M, Kuo B, Nguyen L, et al. ACG clinical guideline: gastroparesis[J]. Am J Gastroenterol, 2022, 117(8): 1197-1220. doi: 10.14309/ajg.0000000000001874
[16] 杨丽惠, 田桢, 周天, 等. 中医外治法治疗消化道肿瘤术后胃瘫综合征研究进展[J]. 中华中医药杂志, 2021, 36(2): 947-950. https://www.cnki.com.cn/Article/CJFDTOTAL-BXYY202102087.htm
[17] 吴人杰, 郑溢声, 林丽珠, 等. 消化道肿瘤术后胃瘫综合征中医治疗策略[J]. 中华中医药学刊, 2022, 40(10): 118-120. https://www.cnki.com.cn/Article/CJFDTOTAL-ZYHS202210027.htm
[18] 敖雪仁, 廖聪, 吴剑纯, 等. 针刺足三里联合中药灌肠治疗消化道肿瘤术后胃瘫综合征临床研究[J]. 国际中医中药杂志, 2022, 44(3): 279-283.
[19] 杨丽惠, 周天, 李星星, 等. 中医外治法治疗消化道肿瘤术后胃瘫综合征的Meta分析[J]. 世界中西医结合杂志, 2019, 14(9): 1216-1221. https://www.cnki.com.cn/Article/CJFDTOTAL-SJZX201909008.htm
[20] Khashab MA, Ngamruengphong S, Carr-Locke D, et al. Gastric per-oral endoscopic myotomy for refractory gastroparesis: results from the first multicenter study on endoscopic pyloromyotomy(with video)[J]. Gastrointest Endosc, 2017, 85(1): 123-128. doi: 10.1016/j.gie.2016.06.048
[21] Pioppo L, Reja D, Gaidhane M, et al. Gastric per-oral endoscopic myotomy versus pyloromyotomy for gastroparesis: an international comparative study[J]. J Gastroenterol Hepatol, 2021, 36(11): 3177-3182. doi: 10.1111/jgh.15599
[22] Camilleri M, Sanders KM. Gastroparesis[J]. Gastroenterology, 2022, 162(1): 68-87. e1.
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