电针配合大承气汤灌肠辅治重症急性胰腺炎胃肠功能障碍的临床观察

郭丹妮; 冯淑兰; 董明国

doi:10.3969/j.issn.1671-038X.2022.04.08

电针配合大承气汤灌肠辅治重症急性胰腺炎胃肠功能障碍的临床观察

- 1.
  广州中医药大学针灸康复临床医学院(广州，510000)
- 2.
  广州中医药大学
- 3.
  广州中医药大学东莞医院

详细信息

通讯作者: 郭丹妮，E-mail：495814331@qq.com

中图分类号: R576

收稿日期: 2022-01-26

刊出日期: 2022-04-15

Clinical observation of electroacupuncture combined with Dachengqi Decoction enema in the treatment of gastrointestinal dysfunction in severe acute pancreatitis

- 1.
  Clinical Medical College of Acupuncture and Rehabilitation, Guangzhou University of Traditional Chinese Medicine, Guangzhou, 510000, China
- 2.
  Guangzhou University of Traditional Chinese Medicine
- 3.
  Dongguang Hospital, Guangzhou University of Traditional Chinese Medicine

More Information

Corresponding author: GUO Danni, E-mail: 495814331@qq.com

Received Date: 26 January 2022

Publish Date: 15 April 2022

摘要

摘要: 目的观察电针配合大承气汤灌肠辅治重症急性胰腺炎胃肠功能障碍的临床疗效。方法按照随机数字表法将2019年5月—2021年2月于广州中医药大学东莞医院就诊的70例重症急性胰腺炎胃肠功能障碍患者分为治疗组和对照组，每组35例。对照组予常规治疗，治疗组在对照组基础上，予以电针配合大承气汤灌肠治疗。对比2组治疗前后白介素-6(IL-6)、肿瘤坏死因子-α(TNF-α)、APACHE Ⅱ评分，记录2组肠鸣音恢复时间、首次排气时间、首次自主排便时间。结果治疗后，2组IL-6、TNF-α均较治疗前降低，且治疗组低于对照组(P< 0.05)。治疗后，2组APACHE Ⅱ评分均较治疗前降低，且治疗组低于对照组(P< 0.05)。治疗组肠鸣音恢复时间、首次排气时间、首次自主排便时间均较对照组短(P< 0.05)。结论电针配合大承气汤灌肠辅治重症急性胰腺炎胃肠功能障碍，可促进胃肠功能恢复，可能与抑制炎症反应有关。
- 电针 /
- 大承气汤 /
- 重症急性胰腺炎 /
- 胃肠功能障碍 /
- 炎症因子
Abstract: Objective To observe the clinical efficacy of electroacupuncture combined with Dachengqi Decoction enema in the treatment of gastrointestinal dysfunction in severe acute pancreatitis.Methods According to the random number table method, 70 patients with gastrointestinal dysfunction of severe acute pancreatitis who were treated in our hospital from May 2019 to February 2021 were divided into treatment group and control group, with 35 cases in each group.The control group received conventional treatment, and the treatment group received electroacupuncture with Dachengqi Decoction enema on the basis of the control group. The scores of interleukin-6(IL-6), tumor necrosis factor-α(TNF-α), and APACHE Ⅱ were compared before and after treatment, and the recovery time of bowel sounds, time of the first exhaust and time to the first spontaneous defecation were recorded in the two groups.Results After treatment, IL-6 and TNF-α in the two groups were lower than those before treatment, and the treatment group was lower in the control group(P< 0.05). After treatment, the APACHE Ⅱ score of the two groups was lower than that before treatment, and the score of the treatment group was lower than that of the control group(P< 0.05). The recovery time of bowel sounds, the first exhaust time and the first spontaneous defecation time in the treatment group were shorter than those in the control group(P< 0.05).Conclusion Electroacupuncture combined with Dachengqi Decoction enema to treat gastrointestinal dysfunction in severe acute pancreatitis can promote the recovery of gastrointestinal function, which may be related to the inhibition of inflammatory response.
- electroacupuncture /
- Dachengqi Decoction /
- severe acute pancreatitis /
- gastrointestinal dysfunction /
- inflammatory factor

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表 1 2组炎症因子比较 pg/mL，X±S

组别	例数	IL-6		TNF-α
组别	例数	治疗前	治疗后	治疗前	治疗后
治疗组	35	95.36±9.18	46.47±6.49¹⁾²⁾	88.36±14.68	38.05±7.24¹⁾²⁾
对照组	35	92.40±8.94	55.63±6.82¹⁾	85.53±15.14	62.35±8.05¹⁾
与同组治疗前比较，¹⁾P＜0.05；与对照组比较，²⁾P＜0.05。

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表 2 2组APACHE Ⅱ评分比较分，X±S

组别	例数	APACHE Ⅱ评分
组别	例数	治疗前	治疗后
治疗组	35	17.26±2.16	7.28±1.46¹⁾²⁾
对照组	35	17.57±2.23	10.44±1.84¹⁾
与同组治疗前比较，¹⁾P＜0.05；与对照组比较，²⁾P＜0.05。

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表 3 2组临床指标比较 h，X±S

组别	例数	肠鸣音恢复时间	首次排气时间	首次自主排便时间
治疗组	35	41.12±8.65¹⁾	51.54±6.46¹⁾	57.36±6.23¹⁾
对照组	35	83.45±7.52	92.52±7.28	98.26±7.30
与对照组比较，¹⁾P＜0.05。

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