荜铃胃痛颗粒联合四联疗法治疗Hp阳性胃溃疡的临床疗效观察

于丽; 巩阳

doi:10.3969/j.issn.1671-038X.2021.03.04

荜铃胃痛颗粒联合四联疗法治疗Hp阳性胃溃疡的临床疗效观察

于丽,
巩阳^,

- 北部战区总医院中医科(沈阳, 110840)

详细信息

通讯作者: 巩阳,E-mail:gongyang126@126.com

中图分类号: R576

收稿日期: 2020-11-03

Observation of the efficacy of quadruple regimen with Biling Weitong granule on pylori-associated gastric ulcer

YU Li,
GONG Yang^,

- Department of Traditional Chinese Medicine, General Hospital of Northern Theater Command, Shenyang, 110840, China

More Information

Corresponding author: GONG Yang, E-mail: gongyang126@126.com

Received Date: 03 November 2020

摘要

摘要: 目的:探讨荜铃胃痛颗粒联合四联疗法对Hp相关胃溃疡患者Hp根除率及上腹痛症状缓解情况。方法:将68例Hp阳性的胃溃疡患者随机分为2组,对照组给予四联疗法,实验组给予四联疗法联合荜铃胃痛颗粒,疗程均为14 d。疗程结束后2组患者继续口服抑酸药6周,完全停药4周后复查¹³C尿素呼气试验及胃镜。观察治疗前后临床疗效,上腹部疼痛缓解情况及Hp根除情况,评价各组的临床总有效率。结果:2组患者Hp根除率分别为84.85%、69.70%,2组之间根除率差异有统计学意义(P<0.05)。且实验组中患者胃脘痛症状缓解率明显高于对照组(P<0.05)。治疗后实验组临床总有效率96.97%,对照组为90.91%,差异有统计学意义(P<0.05)。结论:荜铃胃痛颗粒与四联疗法联合应用对Hp的根除率有明显提高,且可明显增加胃溃疡患者上腹痛症状缓解率,提高临床疗效。
- 胃溃疡 /
- 荜铃胃痛颗粒 /
- 幽门螺杆菌 /
- 中药 /
- 四联疗法
Abstract: Objective: To explore the effect of Biling Weitong combined with quadruple regimen on clinical efficacy and Helicobacter pylori(Hp) clearance rate of pylori-associated gastric ulcer.Methods: Sixty-eight patients with pylori-associated gastric ulcer were selected and randomly divided into observation group and the control group both with 34 cases in each group. The control group were treated quadruple regimen while the observation group were treated Biling Weitong combined with quadruple regimen, both for 14 days. The pantoprazole was continued for 6 weeks after the post-sterilization period. In 4 weeks later, the detection of Hp and gastroscopy were performed again. The clinical efficacy and the eradication rate of pylori were recorded and evaluated before and after treatment.Results: After the treatment, the eradication rate of the Hp in the observation group(84.85%) was apparently higher the the control group(69.70%). The symptom remission rate of abdominal pain was also higher than the control group.Conclusion: Biling Weitong combined with quadruple regimen is a feasible treatment since it can effectively eradicate Hp induced gastric ulcer, improve clinical efficacy.
- gastric ulcer /
- Biling Weitong granule /
- Helicobacter pylori /
- Traditional Chinese Medicine /
- quadruple regimen

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