基于古今医案云平台系统分析李军祥教授治疗溃疡性结肠炎的用药规律

王依; 丁庞华; 谭祥; 李军祥; 施晓军; 张贤翠; 章晓思

doi:10.3969/j.issn.1671-038X.2021.02.01

基于古今医案云平台系统分析李军祥教授治疗溃疡性结肠炎的用药规律

- 1 北京中医药大学(北京, 100029);
- 2 北京中医药大学东方医院脾胃肝胆科
基金项目:
十三五国家重点研发计划(No:2018FYC1705403)

详细信息

通讯作者: 李军祥,E-mail:lijunxiang1226@163.com

中图分类号: R574.62

收稿日期: 2020-08-17

Systematic analysis of drug use regularity of Professor Li Junxiang in the treatment of ulcerative colitis based on ancient and modern medical record cloud platform

- 1 Beijing University of Chinese Medicine, Beijing, 100029, China;
- 2 Department of Gastroenterology, Oriental Hospital of Beijing University of Traditional Chinese Medicine

More Information

Corresponding author: LI Junxiang, E-mail: lijunxiang1226@163.com

Received Date: 17 August 2020

摘要

摘要: 目的:基于古今医案云平台系统分析李军祥教授治疗溃疡性结肠炎的用药规律。方法:随机收集近2年来李军祥教授有效治疗的171例溃疡性结肠炎患者中药处方(一患一方,不分首诊及复诊),将171份处方录入到古今医案云平台系统中,经过医案标准化处理后,建立标准化的数据库,通过频数统计以及数据挖掘方法,分析方剂数据库中各中药用药频率、四气、五味、归经分布及药物功效分布,以明确李军祥教授治疗溃疡性结肠炎的诊疗思路。结果:所采集的171张处方中,涉及药物112种,其中使用频次超过110次的药物有18种;运用关联法则分析药对得到核心处方:木香、苦参、黄连、炮姜、白术、青黛、炙甘草、陈皮、地榆炭、三七、白及、白芍;用药以寒、温两性为主,味多属苦、辛、甘,药物主归脾、胃、肝、大肠、肺、肾经。所用药物主要功效以清热祛湿、清热解毒、温脾补肾、凉血化瘀、行气活血为主。结论:从用药、性味归经、功效主治上体现了李军祥教授治疗溃疡性结肠炎时以脾胃为中心,兼及五脏论治;清温并用,注重阴阳平调;重视清热祛湿解毒,不忘调畅气与血;注重整体辨证论治以提高临床疗效。
- 溃疡性结肠炎 /
- 李军祥 /
- 用药规律
Abstract: Objective: To systematically analyze the drug use regularity of Professor Li Junxiang in the treatment of ulcerative colitis based on the cloud platform of ancient and modern medical records.Methods: The prescriptions of traditional Chinese Medicine in 171 patients with effective ulcerative colitis treated by Professor Li Junxiang in the past two years were randomly collected, and 171 prescriptions were recorded into the ancient and modern medical record cloud platform system. After the standardization of medical records, the standardized database is established, and the frequency, four qi, five flavors, meridian distribution and drug efficacy distribution of traditional Chinese medicine in the prescription database are analyzed by means of frequency statistics and data mining. In order to clarify Professor Li Junxiang's diagnosis and treatment of ulcerative colitis.Results: Among the 171 prescriptions collected, 112 kinds of herbs were involved, of which 18 kinds of herbs were used more than 110 times. The core prescriptions were obtained by analyzing drug pairs by association rule: Radix Rehmanniae, Sophora flavescens, Coptis chinensis, turmeric, Atractylodes macrocephala, Qingdai, licorice, tangerine peel, Diyu charcoal, Panax notoginseng, Baihe, white peony. The main drugs were cold and warm, and the taste was bitter, symplectic and sweet. The drugs mainly belonged to spleen, stomach, liver, large intestine, lung and kidney meridians. The main effects of the drugs are clearing heat and removing dampness, clearing heat and detoxification, warming spleen and tonifying kidney, cooling blood circulation and removing blood stasis.Conclusion: In the treatment of ulcerative colitis, Professor Li takes spleen and stomach as the center and treats the five organs in the treatment of ulcerative colitis from the aspects of herb use, sexual taste, meridian and efficacy in the treatment of ulcerative colitis. Attaching importance to clearing heat and removing dampness and detoxification, keeping an eye on the balance of Yin and Yang, doing not forget to adjust qi and blood, and paying attention to the overall syndrome differentiation and treatment in order to improve the clinical curative effect.
- ulcerative colitis /
- LI Junxiang /
- experience in the use of drugs

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