武汉协和医院354例肝硬化患者流行病学情况及发病的时间规律性研究

朱锐; 吴嫣然; 杨胜兰

doi:10.3969/j.issn.1671-038X.2018.01.05

武汉协和医院354例肝硬化患者流行病学情况及发病的时间规律性研究

- 1 华中科技大学同济医学院附属协和医院中西医结合科湖北武汉 430022;
- 2 华中科技大学同济医学院附属同济医院中西医结合科湖北武汉 430030
基金项目:
国家自然科学基金 (No:81102692)

湖北省自然科学基金 (No:2016CFB684)

武汉市青年科技晨光计划 (No:2017050304010279)

华中科技大学自主创新基金青年教师基金资助 (No:2015QN203)。

详细信息

作者简介:
朱锐,男,副主任医师。研究方向:中西医结合肝病

通讯作者: 杨胜兰,E-mail:yangshenglan@126.com

中图分类号: R575.2

收稿日期: 2017-08-20

Epidemiology and seasonal variation in the onset of cirrhosis:analysis of 354 cases in Wuhan union hospital

- 1 Department of Integrative Traditional Chinese and Western Medicine, Wuhan Union Hospital of Tongji Medical College of Huazhong University of Science and Technology, Wuhan 430022, China;
- 2 Department of Integrative Traditional Chinese and Western Medicine, Wuhan Tongji Hospital of Tongji Medical College of Huazhong University of Science and Technology, Wuhan 430022, China

More Information

Corresponding author: YANG Sheng-lan, E-mail: yangshenglan@126.com

Received Date: 20 August 2017

摘要

摘要: [目的]探讨武汉协和医院354例肝硬化患者流行病学情况及发病时间是否存在时间规律性, 为进一步防治肝硬化提供依据。[方法]回顾性分析武汉协和医院2009年1月~2014年1月354例肝硬化患者的临床资料, 分析其发病的时间规律性。[结果]本组患者男206例, 占58.19%;女148例, 占41.81%;发病年龄51~60岁为高发年龄段;病因以乙型病毒性肝炎最多见, 占45.19%;肝硬化最常见的并发症是门静脉高压 (96.61%);患者就诊的主要原因是上消化道出血 (40.11%)。肝硬化的总体发病时间以3月份最多。[结论]肝硬化存在3月份发病率上升的时间规律性, 乙肝肝硬化是肝硬化的主要病因之一, 防治病毒性肝炎是预防肝硬化的重要手段。积极防治肝硬化并发症上消化道出血是延长患者生命最重要的环节。
- 肝硬化 /
- 流行病学 /
- 季节规律
Abstract: [Objective] To provide basis for the prevention and treatment for cirrhosis via exploring the epidemiology and the possible existence of a seasonal variability in its onset.[Methods] 354 hospitalized cases of cirrhosis, from January 2009 to January 2014, were retrospectively analyzed for seasonal variation.[Results] The data include 206 male patients (58.19%) and 148 female patients (41.81%).High incidence falls in the age range from 51 to 60 years.Viral hepatitis B is the most common cause of cirrhosis (45.19%).The biggest complication (96.61%) is portal hypertension.The patients were mainly hospitalized for upper gastrointestinal hemorrhage (40.11%).There was significant difference in overall incidence of cirrhosis onset time, March had the highest incidence.[Conclusion] Seasonal pattern in the onset of cirrhosis, with a peak in March, is confirmed.Hepatitis B induced cirrhosis is the main cause of the incidence in Hubei, therefore prevention and treatment of viral hepatitis is an important approach for preventing cirrhosis.Prevention and treatment of its complication, upper gastrointestinal hemorrhage, is the key that prolongs life of patients.
- cirrhosis /
- epidemiology /
- seasonal variation

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