十味调脂方联合多烯磷脂酰胆碱治疗NAFLD临床观察

杨倩; 陈宏宇; 张云凤; 杜朋丽

doi:10.3969/j.issn.1671-038X.2017.05.09

十味调脂方联合多烯磷脂酰胆碱治疗NAFLD临床观察

- 1. 河北省中医院肝病科, 河北石家庄 050011;
- 2. 河北医科大学研究生学院, 河北石家庄 050000

详细信息

作者简介:
杨倩,女,主任医师,教授,硕士生导师,主要研究方向:中医肝胆脾胃疾病

通讯作者: 杨倩,E-mail:309297647@qq.com

中图分类号: R575

收稿日期: 2016-11-02

Clinical observation of Shiweitiaozhi decoction combined with Polyene Phosphatidylcholine in treatment of Nonalcoholic fatty liver disease

- 1. Hebei Province Chinese Medicine Hospital, Shijiazhuang 050011, China;
- 2. Graduate School of Hebei Medical University, Shijiazhuang 050000, China

More Information

Corresponding author: YANG Qian, E-mail: 309297647@qq.com

Received Date: 02 November 2016

摘要

摘要: [目的]对联合应用十味调脂方与多烯磷脂酰胆碱治疗非酒精性脂肪性肝病，进行临床疗效观察与分析。[方法]将100例临床确诊为NAFLD符合入选标准的患者随机分为治疗组和对照组，治疗组应用十味调脂方联合多烯磷脂酰胆碱治疗，对照组仅应用多烯磷脂酰胆碱治疗。治疗6个月后，观察对比2组治疗的综合疗效和治疗前后中医症状积分、肝功能、血脂、肝脏超声变化及安全性指标。[结果]治疗后，治疗组患者综合疗效有效率为89.13%，高于对照组70.21%（P<0.05）；治疗组与对照组比较中医证候积分、血脂差异有统计学意义（P<0.05）；较治疗前，2组的肝脏酶学指标差异均有统计学意义（P<0.01），但组间差异无统计学意义（P>0.05）。此外，2组患者均未出现明显不良反应。[结论]临床采用十味调脂方联合多烯磷脂酰胆碱治疗NAFLD，能够提高疗效，且无明显不良反应，值得推广应用。
- 非酒精性脂肪性肝病 /
- 十味调脂方 /
- 多烯磷脂酰胆碱 /
- 临床疗效
Abstract: [Objective] To observe and study the clinical effect of the Shiweitiaozhi Decoction combined with Polyene Phosphatidylcholine in treatment of nonalcoholic fatty liver disease.[Methods] Totally 100 patients with nonalcoholic fatty liver disease were divided into control group and observation group randomly;The former was treated with Shiweitiaozhi decoction and Polyene Phosphatidylcholine while the latter treated with Polyene Phosphatidylcholine only.After 6-month treatment, the changes of comprehensive therapeutic effect, TCM syndrome scoring, blood lipid, liver enzyme indexes, Liver ultrasound and security index were observed.[Results] The effective rate of the treatment group was 89.13%, higher than the control group which was 70.21%(P<0.05).There were statistical differences between the two groups on both TCM syndrome scoring and blood lipid(P<0.05).Compared with pre-treatment, liver enzyme indexes of both the two groups had significant difference(P<0.01), but there was no statistically significant difference between groups(P>0.05).In addition, no obvious adverse reaction occurred in the two groups.[Conclusion] Shiweitiaozhi Decoction combined with Polyene Phosphatidylcholine in the treatment of NAFLD can improve the clinical curative effect without obvious adverse reactions.It is worthy of application and popularization.
- Nonalcoholic fatty liver disease /
- the Shiweitiaozhi Decoction /
- Polyene Phosphatidylcholine /
- clinical effects

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