New insights into inflammatory bowel disease management from the latest American guidelines
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摘要: 炎症性肠病(inflammatory bowel disease,IBD)是一种特发性累及胃肠道的慢性炎症性疾病,由多种病因引起,其发病机制尚未完全明了,有终生复发倾向,且缺乏特效的治疗方法,常需多学科共同诊治和关怀。随着IBD相关的分子基础研究及临床研究快速发展,新的治疗药物如生物制剂、小分子药物快速迭代更新。笔者对美国胃肠病学会近年发表的相关IBD诊治指南及共识进行扼要介绍和述评,以期为IBD的规范化诊治提供帮助。Abstract: Inflammatory bowel disease(IBD) is an idiopathic chronic inflammatory disease involving the gastrointestinal tract, with many underlying causes. The etiology of IBD remains largely unknown. IBD has a tendency of lifelong recurrence, lacking of optimal treatments and requiring multi-disciplinary diagnosis and care. With the rapid development of molecular basic research and clinical research related to IBD, new therapeutic drugs such as biologics and small molecule drugs are rapidly updated. In this review, the author summarizes the current status and progress of drug therapy for IBD based on guidelines or consensus from American Gastroenterological Association recent years, in order to provide help for the standardized management of IBD in China.
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