Research progress in targeted gut microbiota therapy for functional constipation in Traditional Chinese and Western medicine
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摘要: 功能性便秘(functional constipation,FC)是临床上常见的一种消化系统疾病,也可表现为其他疾病的合并症状。微生态失衡是FC的重要特征,通过改善肠道微生态可以有效治疗FC。在肠道微生态治疗方面,两者的作用方式与机制存在着差异。本文结合FC患者肠道微生态变化,对中、西医在FC中的诊断标准、肠道微生态调节机制以及治疗方法进行综述,以期为进一步的研究和临床实践提供参考以及借鉴。Abstract: Functional constipation(FC) is a common digestive disease, which can also present as a complication of other diseases. Microbiome imbalance is an important feature of FC, and FC can be effectively treated by improving the intestinal microbiome. Traditional Chinese and Western medicine have different modes of action and mechanisms in intestinal microecological treatment. This article comprehensively examines alterations observed in the intestinal microecology of FC patients, the diagnostic criteria, mechanisms of intestinal microbiome regulation, and therapeutic approaches adopted by both Traditional Chinese and Western medicine to manage FC. This review seeks to provide a reference and guidance for further research and clinical practice.
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