Analysis of the therapeutic effect of Shugan Jianpi Huoxue therapy combined with abdominal on patients with functional dyspepsia of liver depression and spleen deficiency
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摘要: [目的]分析疏肝健脾活血疗法联合腹针治疗肝郁脾虚型功能性消化不良对促肾上腺皮质激素释放激素 (CRH) 、血清5-羟色胺 (5-HT) 、血清胃泌素 (GAS) 、生长抑素 (SS) 、乙酰胆碱酯酶 (AchE) 及胃动素 (MTL) 的影响。[方法]随机抽取2015年8月~2017年5月我院收治的120例肝郁脾虚型功能性消化不良患者, 依据治疗措施差异分作3组, 各40例, A组施予疏肝健脾活血疗法, B组施予腹针疗法, C组施予疏肝健脾活血疗法联合针刺治疗, 对比分析其CRH、5-HT、GAS、SS、AchE及MTL水平。[结果]治疗14 d及28 d后, C组CRH、5-HT、GAS及SS比A、B组低, 且AchE、MTL比A、B组高, 差异有统计学意义 (P<0.05) ;A、B组间各指标比较差异无统计学意义 (P>0.05) 。[结论]疏肝健脾活血疗法联合腹针有助于改善肝郁脾虚型功能性消化不良疾病, 值得推广。Abstract: [Objective] To analysis the effect of Shugan Jianpi Huoxue decoction combined with abdominal needle in the treatment of functional dyspepsia suffered from liver depression and spleen deficiency syndrome on Corticotropin releasing hormone (CRH) , 5-hydroxytryptamine (5-HT) , Gastrin (GAS) , Somatostatin (SS) , Acetyl cholinesterase (AchE) and Motilin (MTL) . [Methods]Randomly selected 120 cases in August 2015 to May 2017 these patients who suffer from functional dyspepsia suffered from liver depression and spleen deficiency syndrome, mixed on the basis of treatment measures differences divided into three groups, every group have 40 patients, treated with ShuGanJianPiHuoXue decoction as the group A, treated with abdominal needle as the group B, treated with ShuGanJianPiHuoXue decoction combined with abdominal needle as the group C, The levels of CRH, 5-HT, GAS, SS, AchE and MTL were compared and analyzed between these three groups. [Results]After 14 and 28 days of treatment, the levels of CRH, 5-HT, GAS and SS in group C were lower than those of group A and group B. However, the levels of AchE and MTL in group C were significantly higher than those of group A and group B (P<0.05) ; There was no significant difference in the indicators between groups A and B (P>0.05) .[Conclusion]Shugan Jianpi Huoxue Therapy Combined with Abdominal Acupuncture can help to improve the functional dyspepsia of liver stagnation and spleen deficiency, which is worth promoting.
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