Clinical characteristics of inflammation indicators in patients with hypertriglyceridemic pancreatitis
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摘要: [目的]探讨高脂血症性急性胰腺炎相关的炎性指标的特点。[方法]将2014年3月~2015年9月收集入住徐州医科大学附属医院的胰腺炎病例,共计49例,高脂血症胰腺炎13例,非高脂血症性胰腺性36例。检测2组患者的血清淀粉酶、甘油三酯、胆固醇、C-RP、IL-6、降钙素原水平,按照APECH-II系统评估疾病的严重性,以及这些炎性指标与疾病严重程度的相关性。[结果]高脂血症胰腺炎与非高脂血症性胰腺炎比较,总胆固醇,总甘油三酯水平明显升高。血脂水平与疾病的严重程度没有必然联系。高脂血症性胰腺炎的炎症反应指标:中性粒细胞百分比、CRP、IL-6、降钙素原与对照组无明显差异,但与疾病的严重程度相关。[结论]CRP,IL-6,降钙素原这些炎性指标与疾病的严重度有很好的相关性,在预测疾病的严重性方面具有很好的敏感性和特异性。
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关键词:
- 高脂血症性急性胰腺炎 /
- 全身炎症反应综合征 /
- IL-6 /
- c-RP /
- 降钙素原
Abstract: [Objective]Analysis of the Clinical Characteristics of inflammation indicators in patients with hypertriglyceridemic pancreatitis.[Methods]49 AP patients were registered(13 HLAP,36 non-HLAP),from March 2014 to 9 September 2015 in our hospital.Patients were divided into two groups and tested serum amylase,triglyceride(TG),cholesterol(TC),high density of lipoprotein(HDL),lower density lipoprotein(LDL)and C-reactive protein(CRP)、interleukin-6(IL-6),procalcitonin(PCT),estimate the severity of the patients by APECH-II rating system.[Results]Compared with non HLAP groups,TG and TC serum levels in ono-H LAP group are higher.HDL and LDL are identified with non HLAP patients.There is no relative relationship between TG density to severity of pancreatitis.Comparing CRP、PCT、IL-6,there is no significance between the two groups(P＞0.05).These inflammation cytokines has positive relationship to AP severity.[Conclusion]C-RP,IL-6 and PCT have a good correlation with the severity of AP. -
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