Abstract: [Objective] To investigate the effect of Deanxit in improving the psychological prognosis of patients with functional dyspepsia.[Methods] 440 patients with functional dyspepsia who were selected from our hospital from January 2014 to January 2016 were divided into control group and observation group, with 220 patients in each group.The patients in the control group were treated with conventional therapy, and the observation group was treated with Deanxit on the basis of routine therapy.We observed and recorded the clinical symptoms of patients, and evluated the clinical efficacy of the two groups respectively.We also observed and recorded the anxiety state, depressions and the quality of life score before and after treatment as well as adverse reactions in two groups of patients.[Results] In this study, the total effective rate of treatment group was significantly higher than the control group(P<0.05), the difference between the groups was statistically significant.After treatment, SAS score and SDA score in the observation group were significantly lower than the control group(P<0.05), and the difference was statistically significant(P<0.05).The scores of the physical function, mental health, physical pain and general health of the observation group was significantly higher than that of the control group.There was no significant difference between the two groups in the incidence of adverse reactions(P>0.05), and it was not statistically significant.[Conclusion] Deanxit for patients with functional dyspepsia treatment has good clinical curative effect.It can improve the clinical symptoms of patients obviously, reduce depressions, anxieties and other negative emotions, improve the quality of life of patients, and the curative effect is steady, and the side effect is small.