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[1] YASHIRO M.Ulcerative colitis-associated colorectal cancer[J].World J Gastroenterol,2014,20:16389-16397.
[2] EDELBLUM K L,TURNER J R.The tight junction in inflammatory disease:communication breakdown[J].Curr Opin Pharmacol,2009,9:715-720.
[3] BISCHOFF S C,BARBARA G,BUURMAN W,et al.Intestinal permeability--a new target for disease prevention and therapy[J].BMC Gastroenterol,2014,14:189-189.
[4] ZEISSIG S,BURGEL N,GUNZEL D,et al.Changes in expression and distribution of claudin 2,5and 8lead to discontinuous tight junctions and barrier dysfunction in active Crohn's disease[J].Gut,2007,56:61-72.
[5] SCHULZKE J D,BOJARSKI C,ZEISSIG S,et al.Disrupted barrier function through epithelial cell apoptosis[J].Ann N Y Acad Sci,2006,1072:288-299.
[6] MANKERTZ J,SCHULZKE J D.Altered permeability in inflammatory bowel disease:pathophysiology and clinical implications[J].Curr Opin Gastroenterol,2007,23:379-383.
[7] TAKEUCHI K,MAIDEN L,BJARNASON I.Genetic aspects of intestinal permeability in inflammatory bowel disease[J].Novartis Found Symp,2004,263:151-158;discussion 159-163,211-218.
[8] OLSON T S,REUTER B K,SCOTT K G,et al.The primary defect in experimental ileitis originates from a nonhematopoietic source[J].J Exp Med,2006,203:541-552.
[9] VETRANO S,DANESE S.The role of JAM-A in inflammatory bowel disease:unrevealing the ties that bind[J].Ann N Y Acad Sci,2009,1165:308-313.
[10] SHIH D Q,TARGAN S R.Insights into IBD Pathogenesis[J].Curr Gastroenterol Rep,2009,11:473-480.
[11] MANKERTZ J,AMASHEH M,KRUG S M,et al.TNFalpha up-regulates claudin-2expression in epithelial HT-29/B6 cells via phosphatidylinositol-3-kinase signaling[J].Cell Tissue Res,2009,336:67-77.
[12] AL-SADI R,GUO S,YE D,et al.TNF-alpha modulation of intestinal epithelial tight junction barrier is regulated by ERK1/2 activation of Elk-1[J].Am J Pathol,2013,183:1871-1884.
[13] BOUMA G,STROBER W.The immunological and genetic basis of inflammatory bowel disease[J].Nat Rev Immunol,2003,3:521-533.
[14] BRUEWER M,UTECH M,IVANOV A I,et al.Interferon-gamma induces internalization of epithelial tight junction proteins via a macropinocytosis-like process[J].FASEB J,2005,19:923-933.
[15] UTECH M,IVANOV A I,SAMARIN S N,et al.Mechanism of IFN-gamma-induced endocytosis of tight junction proteins:myosin II-dependent vacuolarization of the apical plasma membrane[J].Mol Biol Cell,2005,16:5040-5052.
[16] BOWIE R V,DONATELLO S,LYES C,et al.Lipid rafts are disrupted in mildly inflamed intestinal microenvironments without overt disruption of the epithelial barrier[J].Am J Physiol Gastrointest Liver Physiol,2012,302:G781-G793.
[17] LAUKOETTER M G,BRUEWER M,NUSRAT A.Regulation of the intestinal epithelial barrier by the apical junctional complex[J].Curr Opin Gastroenterol,2006,22:85-89.
[18] LIU X,XU J,MEI Q,et al.Myosin light chain kinase inhibitor inhibits dextran sulfate sodium-induced colitis in mice[J].Dig Dis Sci,2013,58:107-114.
[19] LAPOINTE T K,BURET A G.Interleukin-18facilitates neutrophil transmigration via myosin light chain kinase-dependent disruption of occludin,without altering epithelial permeability[J].Am J Physiol Gastrointest Liver Physiol,2012,302:G343-G351.
[20] SUZUKI T,YOSHINAGA N,TANABE S.Interleukin-6(IL-6)regulates claudin-2 expression and tight junction permeability in intestinal epithelium[J].J Biol Chem,2011,286:31263-31271.
[21] AL-SADI R,YE D,SAID H M,et al.IL-1beta-induced increase in intestinal epithelial tight junction permeability is mediated by MEKK-1activation of canonical NF-kappaB pathway[J].Am J Pathol,2010,177:2310-2322.
[22] PICKERT G,NEUFERT C,LEPPKES M,et al.STAT3links IL-22 signaling in intestinal epithelial cells to mucosal wound healing[J].J Exp Med,2009,206:1465-1472.
[23] ZHENG Y,VALDEZ P A,DANILENKO D M,et al.Interleukin-22mediates early host defense against attaching and effacing bacterial pathogens[J].Nat Med,2008,14:282-289.
[24] DABEK M,FERRIER L,ANNAHAZI A,et al.Intracolonic infusion of fecal supernatants from ulcerative colitis patients triggers altered permeability and inflammation in mice:role of cathepsin G and protease-activated receptor-4[J].Inflamm Bowel Dis,2011,17:1409-1414.
[25] AL-SADI R,BOIVIN M,Ma T.Mechanism of cytokine modulation of epithelial tight junction barrier[J].Front Biosci(Landmark Ed),2009,14:2765-2778.
[26] JOWETT S L,SEAL C J,PEARCE M S,et al.Influence of dietary factors on the clinical course of ulcerative colitis:aprospective cohort study[J].Gut,2004,53:1479-1484.
[27] NEGRONI A,COSTANZO M,VITALI R,et al.Characterization of adherent-invasive Escherichia coli isolated from pediatric patients with inflammatory bowel disease[J].Inflamm Bowel Dis,2012,18:913-924.
[28] MOOSSAVI S,ZHANG H,SUN J,et al.Host-microbiota interaction and intestinal stem cells in chronic inflammation and colorectal cancer[J].Expert Rev Clin Immunol,2013,9:409-422.
[29] MONTROSE D C,SCHERL E J,BOSWORTH B P,et al.S1P(1)localizes to the colonic vasculature in ulcerative colitis and maintains blood vessel integrity[J].J Lipid Res,2013,54:843-851.
[30] HATOUM O A,MIURA H,BINION D G.The vascular contribution in the pathogenesis of inflammatory bowel disease[J].Am J Physiol Heart Circ Physiol,2003,285:H1791-H1796.
[31] CHIDLOW J H,Jr.,SHUKLA D,GRISHAM M B,et al.Pathogenic angiogenesis in IBD and experimental colitis:new ideas and therapeutic avenues[J].Am J Physiol Gastrointest Liver Physiol,2007,293:G5-G18.
[32] CHIDLOW J H,Jr.,LANGSTON W,GREER J J,et al.Differential angiogenic regulation of experimental colitis[J].Am J Pathol,2006,169:2014-2030.
[33] DENG X,SZABO S,KHOMENKO T,et al.Novel pharmacologic approaches to the prevention and treatment of ulcerative colitis[J].Curr Pharm Des,2013,19:17-28.
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