肠道微生态与胆汁淤积的关系

李晓玲, 孙凤霞, 隋京利, 等. 肠道微生态与胆汁淤积的关系[J]. 中国中西医结合消化杂志, 2016, 24(11): 886-887890. doi: 10.3969/j.issn.1671-038X.2016.11.19
引用本文: 李晓玲, 孙凤霞, 隋京利, 等. 肠道微生态与胆汁淤积的关系[J]. 中国中西医结合消化杂志, 2016, 24(11): 886-887890. doi: 10.3969/j.issn.1671-038X.2016.11.19

肠道微生态与胆汁淤积的关系

  • 基金项目:

    国家自然科学基金面上项目(No:81573897)

    北京市卫生系统高层次卫生技术人才项目(No:2013-3-024)

详细信息
    通讯作者: 孙凤霞,E-mail:sunfengxia01969@163.com
  • 中图分类号: R575.6

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  • [1]

    胆汁淤积性肝病诊断治疗专家共识2015年更新专家委员会.胆汁淤积性肝病诊断治疗专家共识:2015年更新[J].中国肝脏病杂志(电子版),2015,7(2):1-10.

    [2]

    孙晋洁,徐旭娟.肠内营养的研究进展[J].世界华人消化杂志,2014(11):1525-1530.

    [3]

    邓芝云,单体栋,张方信.重症肝炎与肠黏膜屏障[J].世界华人消化杂志,2010,18(35):3761-3766.

    [4]

    ZHOU K,JIANG M,LIUY,et al.Effect of bile pigments on the compromised gut barrier function in a rat model of bile duct ligation[J].PLoS One,2014,9:e98905.

    [5]

    RIDLON J M,HARRIS S C,BHOWMIK S,et al.Consequences of bile salt biotransformations by intestinal bacteria[J].Gut Microbes,2016,7:22-39.

    [6]

    TSUJI M,SUZUKI K,KINOSHITA K,et al.Dynamic interactions between bacteria and immune cells leading to intestinalIgA synthesis[J].Semin Immunol,2008,20:59-66.

    [7]

    KANG W,KUDSK K A.Is there evidence that the gut contributes to mucosal immunity in humans?[J].JPEN J Parenter Enteral Nutr,2007,31:246-258.

    [8]

    杨连祥.梗阻性黄疸大鼠肠黏膜ET-1,iNOS的表达及肠黏膜屏障功能的实验研究[D].河北:河北联合大学,2011.

    [9]

    ZHANG C,XU Y G,DUAN X N,et al.Role of granulocyte colony-stimulating factor in paclitaxel-induced intestinal barrier breakdown and bacterial translocation in rats[J].Chin Med J(Engl),2011,124:1870-1875.

    [10]

    YANG R,HARADA T,LI J,et al.Bile modulates intestinal epithelial barrier function via an extracellular signal related kinase 1/2dependent mechanism[J].Intensive Care Med,2005,31:709-717.

    [11]

    ASSIMAKOPOULOS S F,SCOPA C D,CHARONIS A,et al.Experimental obstructive jaundice disrupts intestinal mucosal barrier by altering occludin expression:beneficial effect of bombesin and neurotensin[J].J Am Coll Surg,2004,198:748-757.

    [12]

    陈振勇,冯贤松,周有生.梗阻性黄疸大鼠肠黏膜上皮紧密连接蛋白和MLCK的研究[J].中国普通外科杂志.2008,17(2):140-144.

    [13]

    STELIOS F,ASSIMAKOPOULOS,ATHANASSIOS C,et al.Intestinal epithelial cell proliferation,apoptosis and expression of tight junction proteins in patients with obstructive jaundice[J].Eur J Clin Invest,2011,41:117-125.

    [14]

    胡玉莲,王晓东,黄志华.实验性急性肝内胆汁淤积幼年大鼠胃肠消化间期移行性肌电复合波的变化[J].世界华人消化杂志,2006,14(32):3098-3102.

    [15]

    ASSIMAKOPOULOS S F,VAGIANOS C E,PATSOUKIS N,et al.Evidence for intestinal oxidative stress in obstructive jaundice-induced gut barrier dysfunction in rats[J].Acta Physiol Scand 2004;180:177-185.

    [16]

    PANDE C,KUMAR A,SARIN S K.Small-intestinal bacterial overgrowth in cirrhosis is related to the severity of liver disease[J].Aliment Pharmacol Ther,2009,29:1273-1281.

    [17]

    GUNNARSDOTTIR S A,SADIK R,SHEV S,et al.Small intestinal motility disturbances and bacterial overgrowth in patients with liver cirrhosis and portal hypertension[J].Am J Gastroenterol,2003,98:1362-1370.

    [18]

    YAMAGUCHI J,TOLEDO A,BASS B L,et al.Taurodeoxycholate increases intestinal epithelial cell proliferation through c-myc expression[J].Surgery,2004,135:215-221.

    [19]

    TURNER D J,ALAISH S M,ZOU T,et al.Bile salts induce resistance to apoptosis through NF-kappaB-mediated XIAP expression[J].Ann Surg,2007,245:415

    [20]

    YANG R,HARADA T,LI J,et al.Bile modulates intestinal epithelial barrier function via an extracellular signal related kinase 1/2dependent mechanism.[J].Intensive Care Med,2005,31:709-717.

    [21]

    陈意生,史景泉.多器官功能障碍综合征的病理学变化[J].诊断病理学杂志,2014,21(6):355-360.

    [22]

    吴孟超,吴在德.黄家驷外科学[M].7版.北京:人民卫生出版社,2008:400-429.

    [23]

    KURU B,DINC S,ALTINOK G,et al.Effect of different enteral nutrients on bacterial translocation in experimental obstructive jaundice[J].Eur Surg Res,2004,36:45-52.

    [24]

    LI W,CHAN A C,LAU Y,et al.Superoxide and nitric oxide production by Kupffer cells in rats with obstructive jaundice:effect of internal and external drainage[J].J Gastroenterol Hepatol,2004,19:160-165.

    [25]

    SANO T,AJIKI T,TAKEYAMA Y,et al.Internal biliary drainage improves decreased number of gut mucosal T lymphocytes and MAd-CAM-1expression in jaundiced rats[J].Surgery,2004,136:693-699.

    [26]

    赵增虎,李成云,张建宇,等.阻塞性黄疸对肠道微生态环境影响的实验研究[J].山东医药,2006,46(31):19-20.

    [27]

    李兰娟.感染与微生态学[M].北京:人民卫生出版社,2002:295-300.

    [28]

    WHITE J S,HOPER M,PARKS R W,et al.The probiotic bacterium lactobacillus plantarum species 299reduces intestiral permeability in experimental biliary obstruction[J].Lett Appl Microbiol,2006,42:19-23.

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出版历程
收稿日期:  2016-06-08

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