幽门螺杆菌的3种临床实用检测方法的比较分析

王兴艳

doi:10.3969/j.issn.1671-038X.2016.10.14

幽门螺杆菌的3种临床实用检测方法的比较分析

王兴艳^,

- 徐州矿山医院内三科, 江苏徐州 221006

详细信息

作者简介:
王兴艳,主治医师,从事消化疾病方面研究

通讯作者: 王兴艳,E-mail:ljw135125@163.com

中图分类号: R573.6

收稿日期: 2016-04-25

Comparison of three methods for Helicobacter pylorus detection

WANG Xing-yan^,

- Department of;

More Information

Corresponding author: WANG Xing-yan, E-mail: ljw135125@163.com

Received Date: 25 April 2016

摘要

摘要: [目的]对幽门螺杆菌(Hp)的3种临床实用检测方法进行比较分析。[方法]收集我院符合要求的患者280例,胃镜检查诊断进行分类,同时行¹³C尿素呼气试验、快速尿毒酶试验和病理组织学检测,比较3种检测方法的敏感性及特异性。[结果]280例患者中Hp感染172例,感染率为61.4%,其中胃窦炎伴糜烂Hp感染率>消化性溃疡Hp感染率>慢性萎缩性胃炎Hp感染率>慢性浅表性胃炎Hp感染率。¹³C尿素呼气试验、快速尿毒酶试验和病理组织学检测敏感性及特异性分别为:97.10%、86.00%、95.90%和96.78%、85.36%、97.14%;阳性率分别为61.07%、59.29%、59.28%。[结论]¹³C尿素呼气试验敏感度高,能反映Hp感染状况,整个试验过程需要的时间短,患者无其他任何不适,是这3种临床实用检查方法中最理想的检测方法。
- 幽门螺杆菌 /
- 临床实用 /
- 检测方法 /
- 敏感性
Abstract: [Objective]To evaluate three staining methods for detection of Helicobacter pylorus gastric biopsy specimens.[Methods]280 cases of patients were collected corresponding to diagnosis standards in hospital of Xuzhoukuangshuan,gastroscopy diagnosis classification,¹³C urea breath test,rapid urease test and histopathology test were measured at the same time,the sensitivity and specificity of the three methods were compared.[Results]172 participants were diagnosed as Hp infection in total 280 patients,the infection rate was 61.4%.The HP infection rate of antral gastritis with erosion > Hp infection rate of peptic ulcer>Hp infection rate of chronic atrophic gastritis> Hp infection rate of chronic superficial gastritis.The sensitivity and specificity of ¹³C urea breath test,rapid urease test and histological detection were:97.10%,86.00%,95.90% and 96.78%,85.36%,97.14%.The positive rates were 61.07%,59.29% and 59.28%.[Conclusion]¹³C urea breath test is more sensitive than other two methods and can reflect the status of HP infection effectively.The whole test process requires a short time,and patients did not feel uncomfortable.¹³C urea breath test is the most ideal detection method in the three kinds of clinical practical examination method.
- Helicobacter pylori /
- clinical application /
- detection method /
- sensitivity

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