柴胡温胆汤联合奥美拉唑治疗胃食管反流病胆热犯胃证的疗效分析

张丽进; 赵淑芳

doi:10.3969/j.issn.1671-038X.2015.05.11

柴胡温胆汤联合奥美拉唑治疗胃食管反流病胆热犯胃证的疗效分析

张丽进^1, ,,
赵淑芳²

- 1 东阳市人民医院巍山分院药剂科, 浙江东阳 322109;
- 2 东阳市人民医院巍山分院中医科, 浙江东阳 322109

详细信息

作者简介:
张丽进,女,副主任药师,研究方向:医院药学、临床药学

通讯作者: 张丽进,E-mail:zli.jin@163.com

中图分类号: R56

收稿日期: 2014-12-09

Efficacy of Radix bupleuri Wendan Decoction combined with omeprazole in the treatment of bilious fever in gastroesophageal reflux disease

ZHANG Li-jin^1, ,,
ZHAO Shu-fang²

- 1 Department of Pharmacy, Weishan Division, Dongyang People's Hospital, Dongyang 322109, China;
- 2 Department of Traditional Chinese Medicine, Weishan Division, Dongyang People's Hospital, Dongyang 322109, China

More Information

Corresponding author: ZHANG Li-jin, E-mail: zli.jin@163.com

Received Date: 09 December 2014

摘要

摘要: [目的]探究与分析柴胡温胆汤联合奥美拉唑治疗胃食管反流病胆热犯胃证的疗效。[方法]选取我院自2013年4月~2013年12月收治的180例胃食管反流病胆热胃证的患者作为研究对象,将其按照就诊顺序分为观察组和对照组,观察组患者采用柴胡温胆汤联合奥美拉唑(国药准字H19991118)治疗,对照组采用单独奥美拉唑治疗。观察并分析2组治疗效果。[结果]观察组临床疗效总有效率占比96.67%(87/90),与对照组的88.89%(80/90)相比占显著优势,差异有统计学意义,P＜0.05。2组患者经治疗后胃镜下食管黏膜炎症情况,观察组有效率占比94.44%(85/90)与对照组的85.56%(77/90)相比差异显著,差异有统计学意义,P＜0.05。观察组呕吐、反酸、口苦咽干、嗳气、吞咽困难等情况均较对照组有显著的改善,差异有统计学意义,P＜0.05。[结论]柴胡温胆汤联合奥美拉唑治疗胃食管反流病胆热犯胃证具有良好的临床效果,值得临床应用。
- 柴胡温胆汤 /
- 奥美拉唑 /
- 胃食管反流病 /
- 胆热犯胃证 /
- 疗效
Abstract: [Objective] To explore and analyze the efficacy of radix bupleuri Wendan decoction combined with omeprazole in the treatment of bilious fever in gastroesophageal reflux disease(GERD).[Methods] One hundred and eighty GERD patients with bilious fever in our hospital from Apr 2013 to Dec 2013 were selected as the study objects,and divided into observation group and control group according to their admission order. The observation group was treated by combined bupleuri Wendan decoction and omeprazole(approved by Sinopharm H19991118),while the control group was treated by omeprazole only. The efficacy of two groups was observed and analyzed. [Results] The total effective rate of clinical efficacy of observation group was(96.67%), which was significantly higher than control group(88.89%),and the difference was statistically significant(P＜0.05). While comparing the esophageal mucosa observed by gastroscope,the total effective rate was 94.44% in observation group and 85.56% in control group,and the difference between two groups was statistically significant (P＜0.05). And symptoms such as emesis,sour regurgitation,bitter mouth and dry throat,dysphagia and so on of observation group had improved significantly compared to control group,and the difference was statistically significant (P＜0.05).[Conclusion] Radix bupleuri Wendan decoction combined with omeprazole has good clinical efficacy in the treatment of bilious fever in GERD,which is worthy of being applicated in clinic.
- radix bupleuri Wendan decoction /
- omeprazole /
- gastroesophageal reflux disease /
- bilous fever /
- efficacy

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