10天序贯疗法和传统三联疗法根除幽门螺杆菌的疗效比较

详细信息

收稿日期: 2013-08-13

Received Date: 13 August 2013

摘要: [目的]比较10 d序贯疗法与传统三联疗法根除幽门螺杆菌(Hp)的疗效。[方法]选取78例¹⁴C-尿素呼气试验阳性病例,随机分为2组:治疗组(39例)前5天予埃索美拉唑、阿莫西林,后5天予埃索美拉唑、克拉霉素、替硝唑治疗;对照组(39例)予埃索美拉唑、克拉霉素、阿莫西林治疗10 d。疗程结束1个月后行¹⁴C-尿素呼气试验检测。[结果]治疗组¹⁴C-尿素呼气试验检测阴性者37例,阳性者2例,根除率为94.87%;对照组¹⁴C-尿素呼气试验检测阴性者32例,阳性者7例,根除率为82.05%,2组Hp根除率比较差异有统计学意义(P<0.05),2组不良反应比较差异无统计学意义。[结论] 10 d序贯疗法治疗Hp感染的根除率较传统三联疗法高。
- 胃疾病 /
- 序贯疗法 /
- 三联疗法 /
- 幽门螺杆菌

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